Postural Hypotension with or without symptoms (e.g. dizziness) may develop within a few hours following administration of Alfuzosin. As with all alpha-blockers, there is a potential for syncope. 

IFIS observed during cataract surgery in some patients on or previously treated with alpha-1 blockers.

The risk of this event with Alfuzosin appears very low.

Ophthalmic surgeons should be informed in advance of cataract surgery of current or past use of alpha-1-blockers as IFIS may lead to increased procedural complications.

The Ophthalmologists should be prepared for possible modifications to their surgical technique.

IFIS: Intraoperative Floppy Iris Syndrome

4. Product information Alfuzosin

Patients should be warned of the possible occurrence of syncope and should avoid situations where injury could result in syncope. Care should be taken when Alfuzosin is administered to patients with symptomatic Hypotension or patients who have had a hypotensive response to other medications.

Alfuzosin HCl is contraindicated:

In patients with moderate or severe hepatic insufficiency

When administered with potent CYP3A4 inhibitors and therefore, should not be used in combination with drugs such as Ketoconazole, Itraconazole and Ritonavir.

Pregnancy and Lactation

Known hypersensitivity to Alfuzosin or any other ingredients of the formulation

History of Orthostatic Hypotension

4. Product information Alfuzosin