Product Information
Patient Information leafletComposition:
Methyl Salicylate IP 100 mg
Menthol IP 50 mg
Capsaicin USP 0.25 mg
in a water soluble base .
Storage:
Store below 25°C. Protect from light. Do not refrigerate.Unique Identification Code:
8901148204805Manufacturing License Number:
M.L.L/07/460/MNBOverview
- Fever
- Pain
- Joint pains
The usual adult dose is 100 mg twice daily, orally.
Nise Gel is for external use only. Take a small amount of Nise Gel on the finger and apply as a thin layer on the clean and dry affected area and surrounding skin. Avoid contact with the eyes, mouth, or nose. If accidental contact occurs, rinse thoroughly with water. Be sure to wash your hands before and after application.Nise Gel is for external use only. Take a small amount of Nise Gel on the finger and apply as a thin layer on the clean and dry affected area and surrounding skin. Avoid contact with the eyes, mouth, or nose. If accidental contact occurs, rinse thoroughly with water. Be sure to wash your hands before and after application.
- While using Nise Gel, you are recommended to tell your doctor if you are allergic to the active substances of Nise Gel and if you have kidney, liver, or heart disease, diabetes, asthma, high blood pressure, bleeding in the stomach or intestines, stomach ulcers, and edema.
- Avoid using Nise Gel on cuts, wounds, or damaged skin.
- Avoid consuming alcohol while using it to reduce the risk of stomach bleeding.
- Do not apply heat or tightly wrap the treated area.
- Use only as directed, and avoid excessive or prolonged application to prevent adverse effects.
Common side effects :
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Gastrointestinal disturbances: epigastric pain, heartburn, nausea, diarrhea, vomiting
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Skin reactions: rash, itching (pruritus)
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Dizziness
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Drowsiness
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Headache
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Excessive sweating or flushing
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Sleep disorder.
Caution with Warfarin:
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Be careful when using nimesulide with warfarin (check DRUG INTERACTIONS).
Liver Function:
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Nimesulide is processed in the liver.
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Patients with moderate to severe liver issues should not use nimesulide due to risk of drug buildup.
Kidney Function:
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There are reports of kidney failure with nimesulide, but not conclusively linked.
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Use nimesulide with caution in patients with kidney problems.
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Avoid nimesulide in patients with severe kidney impairment.
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Those with weak kidneys, heart failure, liver cirrhosis, metabolic disorders, or dehydration are more sensitive to nimesulide and should use it cautiously.
Asthmatic Patients:
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Use nimesulide with caution in patients with asthma, similar to other NSAIDs.
Patient Guidance
Manage your health
Manage your health
- Follow the dosage: Apply a thin layer of Nise Gel to the affected area as directed by your doctor. Do not rub it into the skin.
- Avoid sensitive areas: Keep the gel away from your eyes, ears, nose, and mouth.
- Monitor for side effects: If you notice any irritation, redness, or rash, discontinue use and consult your doctor.
- Store properly: Keep Nise Gel below 25°C and out of reach of children.
- Consult your doctor: Always use Nise Gel under the guidance of a healthcare professional, especially if you have any pre-existing conditions or are taking other medications.
Frequently asked questions
How does Nise Gel work?
Nise Gel is a combination of: Nimesulide, Capsaicin, Methyl salicylate‚ and one cooling agent (Menthol). Nimesulide and Methyl salicylate works by blocking the release of certain chemical messengers in the brain responsible for causing pain and symptoms of inflammation such as redness and swelling. Capsaicin works by affecting the chemical messenger in the brain (neurotransmitter) that transmits pain signals to the brain, thereby reducing the perception of pain. Menthol acts as a cooling agent that relieves pain initially by cooling the skin, followed by warming it up. Cooling and warming up distracts from the pain and helps improve blood circulation.
In which conditions should I avoid using Nise Gel?
You are recommended to avoid using Nise Gel if you have had any recent bypass heart surgery, heart attack, stroke, gastrointestinal bleeding (bloody stool), or ulcer of the stomach or intestine. Elderly (more than 65 years of age) or smokers are at greater risk of having gastrointestinal bleeding, so they should use Nise Gel with caution
Can I apply Nise Gel on wounds?
No, you are not recommended to apply Nise Gel on wounds, cuts, burn, rash, infected areas or peeling skin. However, please consult a doctor before using Nise Gel.
Does Nise Gel cause skin irritation?
Yes, Nise Gel may cause skin irritation at the site of application as a common side effect. It is not necessary for everyone using Nise Gel to experience this side effect. However, if the irritation persists or worsens, please consult a doctor.
Is Nise Gel safe for heart failure patients?
Patients with heart failure are not advised to take Nise Gel because painkillers may alter blood substance levels and make blood clots more likely. These blood clots have the potential to block and constrict your heart's artery, leading to a heart attack.
Can I take shower immediately after applying Nise Gel?
You are recommended to take a shower, bathe or wash the treated area of skin after 1 hour of applying Nise Gel for effective results.
Does Nise Gel cure arthritis?
No, Nise Gel does not cure arthritis. Nise Gel is only used to relieve symptoms of arthritis-like joint pain, swelling and stiffness.
Is Nise Gel a steroid?
No, Nise Gel, is not a steroid. It belongs to the class of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).
Is Nise Gel banned?
No, Nise Gel is not banned in India.
Is Nise Gel an antibiotic?
No, Nise Gel is not an antibiotic. It contains capsaicin, menthol methyl salicylate, and nimesulide as its active substances, used to relieve pain and inflammation associated with conditions like muscle aches, joint pain, and sprains.
